[Permanent link] [Permanent link] Cultured motor neuron (red) on a monolayer of astrocytes

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Cultured motor neuron (red) on a monolayer of astrocytes

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A cultured motor neuron (red) on a monolayer of astrocytes (green). These neurons have calcium-permeable AMPA-type glutamate receptors and are vulnerable to excitotoxicity: damage from excessive calcium influx. Astrocytes induce motor neurons to express a receptor subunit that prevents calcium entry. See the article by Van Damme et al. on pages 14825–14830.


Photographer(s)

Ludo Van Den Bosch and Maarten Dewil


Citation

PNAS, Astrocytes regulate GluR2 expression in motor neurons and their vulnerability to excitotoxicity, Philip Van Damme et al.